Samuel Klein Selected Research

Palmitates

10/2020	Obesity Is Associated With Increased Basal and Postprandial β-Cell Insulin Secretion Even in the Absence of Insulin Resistance.
1/2020	Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease.
1/2017	HIV infection does not prevent the metabolic benefits of diet-induced weight loss in women with obesity.
9/2014	Diurnal variation in insulin sensitivity of glucose metabolism is associated with diurnal variations in whole-body and cellular fatty acid metabolism in metabolically normal women.
7/2012	Relationship between adipose tissue lipolytic activity and skeletal muscle insulin resistance in nondiabetic women.
3/2012	Does rimonabant independently affect free fatty acid and glucose metabolism?
2/2012	Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects.
1/2009	Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content.
2/2008	Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease.
5/2006	Gastric bypass surgery improves metabolic and hepatic abnormalities associated with nonalcoholic fatty liver disease.

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Samuel Klein Research Topics

Disease

84	Insulin Resistance 10/2022 - 05/2004
76	Obesity 10/2022 - 04/2002
69	Weight Loss (Weight Reduction) 01/2021 - 06/2002
24	Type 2 Diabetes Mellitus (MODY) 10/2022 - 02/2002
20	Non-alcoholic Fatty Liver Disease 10/2022 - 05/2006
16	Body Weight (Weight, Body) 10/2022 - 06/2002
15	Inflammation (Inflammations) 01/2021 - 05/2006
12	Overweight 11/2021 - 06/2002
9	Hyperinsulinism (Hyperinsulinemia) 01/2021 - 02/2002
8	Glucose Intolerance 01/2022 - 08/2004
7	Abdominal Obesity 12/2008 - 04/2002
5	Hyperglycemia 01/2022 - 04/2003
5	Weight Gain 01/2022 - 02/2015
5	Cardiovascular Diseases (Cardiovascular Disease) 02/2015 - 06/2002
5	Dyslipidemias (Dyslipidemia) 08/2012 - 05/2005
4	Fibrosis (Cirrhosis) 10/2022 - 12/2020
4	Prediabetic State (Prediabetes) 11/2021 - 10/2019
4	Neoplasms (Cancer) 01/2021 - 12/2006
4	Coronary Disease (Coronary Heart Disease) 12/2008 - 05/2003
3	Metabolic Diseases (Metabolic Disease) 01/2019 - 06/2008
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2014 - 06/2008
2	Liver Diseases (Liver Disease) 01/2022 - 01/2021
2	Hypoxia (Hypoxemia) 01/2019 - 11/2012
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 07/2014
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2011 - 10/2006

Drug/Important Bio-Agent (IBA)

70	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 02/2002
57	Insulin (Novolin)FDA Link 01/2022 - 02/2002
23	Triglycerides (Triacylglycerol)IBA 10/2022 - 02/2008
21	Fatty Acids (Saturated Fatty Acids)IBA 01/2016 - 02/2002
19	LipidsIBA 01/2021 - 06/2002
18	Proteins (Proteins, Gene)FDA Link 10/2022 - 04/2002
13	IsotopesIBA 01/2019 - 04/2002
12	PalmitatesIBA 10/2020 - 02/2002
11	Nonesterified Fatty Acids (NEFA)IBA 01/2017 - 03/2003
10	very low density lipoprotein triglycerideIBA 10/2022 - 03/2003
10	VLDL LipoproteinsIBA 01/2016 - 04/2003
7	Therapeutic UsesIBA 10/2022 - 03/2011
7	AdiponectinIBA 01/2021 - 06/2004
6	CarbohydratesIBA 01/2022 - 05/2009
5	Amino Acids FDA Link 01/2022 - 04/2002
5	Branched-Chain Amino AcidsIBA 01/2021 - 08/2013
4	Sucrose (Saccharose)IBA 10/2021 - 05/2014
4	CytokinesIBA 01/2021 - 03/2007
4	HDL CholesterolIBA 11/2016 - 06/2008
4	Orlistat (Xenical)FDA Link 01/2008 - 06/2002
3	Messenger RNA (mRNA)IBA 01/2021 - 02/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
3	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 11/2013
3	Leucine (L-Leucine)FDA Link 05/2018 - 10/2006
3	Interleukin-6 (Interleukin 6)IBA 01/2018 - 06/2004
3	Apolipoprotein B-100 (Apo B 100)IBA 11/2016 - 03/2003
3	C-Reactive ProteinIBA 09/2016 - 06/2004
3	C-PeptideIBA 07/2015 - 06/2008
3	Glucagon-Like Peptide 1 (GLP 1)IBA 07/2015 - 10/2012
3	LeptinIBA 07/2014 - 05/2011
3	Lipoproteins (Lipoprotein)IBA 06/2012 - 03/2003
3	Glycerol (Glycerine)FDA LinkGeneric 05/2011 - 02/2002
2	Biological ProductsIBA 01/2022 - 04/2016
2	Nicotinamide MononucleotideIBA 11/2021 - 01/2021
2	CollagenIBA 01/2021 - 05/2006
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2021
2	gamma-Aminobutyric Acid (GABA)IBA 01/2021 - 01/2021
2	Plasminogen Activator Inhibitor 1IBA 01/2021 - 12/2020
2	Oxygen (Dioxygen)IBA 12/2020 - 01/2019
2	ChemokinesIBA 12/2020 - 03/2007
2	Glucagon (Glukagon)FDA Link 11/2019 - 06/2008
2	fibroblast growth factor 21IBA 10/2017 - 01/2017
2	CalciumIBA 02/2016 - 07/2012
2	Hormones (Hormone)IBA 07/2015 - 12/2006
2	AntioxidantsIBA 09/2014 - 03/2014
2	Uric Acid (Urate)IBA 09/2014 - 03/2014
2	Bile Acids and Salts (Bile Acids)IBA 04/2013 - 08/2010
2	ginsenoside ReIBA 11/2012 - 05/2011
2	Niacin (Nicotinic Acid)FDA LinkGeneric 08/2012 - 06/2010
2	HDL LipoproteinsIBA 01/2011 - 12/2008
2	Insulin-Like Growth Factor I (IGF-1)IBA 03/2010 - 10/2008
2	AdipokinesIBA 12/2009 - 04/2007
2	sibutramine (Meridia)FDA Link 01/2008 - 12/2004
2	Chemotactic FactorsIBA 03/2007 - 05/2006
2	Protease Inhibitors (Protease Inhibitor)IBA 03/2007 - 05/2005
2	Metformin (Glucophage)FDA LinkGeneric 03/2003 - 07/2002
2	Troglitazone (Rezulin)FDA Link 03/2003 - 02/2002
2	Lipase (Acid Lipase)FDA Link 07/2002 - 06/2002
1	Phospholipases (Phospholipase)IBA 10/2022
1	EnzymesIBA 10/2022

Therapy/Procedure

33	Therapeutics 01/2021 - 02/2002
19	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2020 - 05/2006
10	Glycemic Control 10/2022 - 06/2002
8	Bariatric Surgery 01/2022 - 01/2008
8	Caloric Restriction 11/2017 - 04/2004
6	Drug Therapy (Chemotherapy) 01/2022 - 12/2004
5	Fat-Restricted Diet (Diet, Fat Restricted) 10/2019 - 11/2004
4	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 10/2019 - 05/2003
3	Gastrectomy 12/2017 - 08/2014
3	Diet Therapy (Therapy, Diet) 12/2009 - 03/2007
2	Injections 01/2021 - 03/2013
2	Aftercare (After-Treatment) 05/2011 - 08/2010
2	Lipectomy (Liposuction) 12/2008 - 06/2004
2	Exercise Therapy (Therapy, Exercise) 06/2008 - 04/2006
2	Highly Active Antiretroviral Therapy (HAART) 03/2007 - 05/2005